Ligand modulated Heck vinylation with molecular oxygen as oxidant
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چکیده
Palladium(II)-mediated vinylic substitutions of organoboronic acids are known as oxidative Heck reactions and up to now there has been no ligand-supported oxidative Heck protocol, which would help in the development of new selective and efficient reactions. Larhed et al. from the University of Uppsala have developed a novel protocol in which aryl boronic acids are coupled to a variety of olefins, employing a phenanthroline type ligand and molecular oxygen as reoxidant (Chem. Commun. 2004, 218–219).
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